-
Vorinostat (rINN), also
known as
suberoylanilide hydroxamic acid (suberoyl+anilide+hydroxamic acid
abbreviated as SAHA), is a
member of a
larger class...
-
Larotaxel Pa****axel
Taxotere Tesetaxel Ixabepilone Entinostat Romidepsin Vorinostat Zabadinostat Belotecan Camptothecin Exatecan Gimatecan Irinotecan Topotecan...
- "second-generation" HDIs
included the
hydroxamic acidsĀ :
trichostatin A,
vorinostat (SAHA),
belinostat (PXD101), resminostat, abexinostat, givinostat, LAQ824...
- metabolites.
Disulfiram is also
being investigated in
combination with
vorinostat,
another investigational latency reversing agent, to
treat HIV. "FDA-sourced...
- cells.
Vorinostat is
structurally related to
trichostatin A and used to
treat cutaneous T cell lymphoma.
Histone deacetylase inhibitor Vorinostat (SAHA)...
-
Tucidinostat Valnoctamide Valproic acid (valproate)
Valproate pivoxil Valproate semisodium Valpromide Vorinostat (SAHA) See also: Receptor/signaling modulators...
- Drug
Administration (FDA),
Vorinostat represents a new
category for
anticancer drugs that are in development.
Vorinostat targets histone acetylation...
-
component of ERĪ±
silencing in
human breast cancer cells.
Approved usage:
Vorinostat was
licensed by the U.S. FDA in
October 2006 for the
treatment of cutaneous...
-
involving the skin. It is only
available at a few institutions. Romidepsin,
vorinostat and a few
others are a second-line drug for
cutaneous T-cell lymphoma...
-
compared the
effect of
romidepsin to
another histone deacetylase inhibitor,
Vorinostat A
study involving romidepsin in an
animal study that
showed that a brief...
