-
Vorinostat (rINN), also
known as
suberoylanilide hydroxamic acid (suberoyl+anilide+hydroxamic acid
abbreviated as SAHA), is a
member of a
larger class...
-
Larotaxel Pa****axel
Taxotere Tesetaxel Ixabepilone Entinostat Romidepsin Vorinostat Zabadinostat Belotecan Camptothecin Exatecan Gimatecan Irinotecan Topotecan...
- "second-generation" HDIs
included the
hydroxamic acids :
trichostatin A,
vorinostat (SAHA),
belinostat (PXD101), resminostat, abexinostat, givinostat, LAQ824...
- cells.
Vorinostat is
structurally related to
trichostatin A and used to
treat cutaneous T cell lymphoma.
Histone deacetylase inhibitor Vorinostat (SAHA)...
- metabolites.
Disulfiram is also
being investigated in
combination with
vorinostat,
another investigational latency reversing agent, to
treat HIV. "FDA-sourced...
- Drug
Administration (FDA),
Vorinostat represents a new
category for
anticancer drugs that are in development.
Vorinostat targets histone acetylation...
- chemotherapies,
local superficial radiotherapy, the
histone deacetylase inhibitor vorinostat,
total skin
electron radiation, photopheresis,
systemic therapies (e.g...
-
Denileukin diftitox (Ontak) (2000)
Bexarotene (Targretin) a
retinoid (2006)
Vorinostat (Zolinza) a
hydroxymate histone deacetylase (HDAC)
inhibitor (2009) Romidepsin...
- HDIs).
Marks and
others found that
drugs such as
Trichostatin A and SAHA (
vorinostat) can
serve as
anticancer agents.
Marks published more than 400 scientific...
-
Tucidinostat Valnoctamide Valproic acid (valproate)
Valproate pivoxil Valproate semisodium Valpromide Vorinostat (SAHA) See also: Receptor/signaling modulators...
