-
Vismodegib, sold
under the
brand name Erivedge, is a
medication used for the
treatment of basal-cell
carcinoma (BCC). The
approval of
vismodegib on January...
- Food and Drug
Administration (FDA) for
cancer treatment.
These include vismodegib and sonidegib, both
inhibitors of
Smoothened (SMO),
which are
being used...
- by the FDA;
vismodegib in 2012, and
sonidegib in 2015.
Vismodegib was the
first Shh
pathway drug
approved for
treating cancer.
Vismodegib was designed...
-
Teniposide Tafluposide Bortezomib Erlotinib Gefitinib Imatinib Vemurafenib Vismodegib Azacitidine Azathioprine Capecitabine Cladribine Clofarabine Cytarabine...
- YW,
Macdonald JB,
Nelson SA,
Sekulic A (December 2017). "Treatment of
vismodegib-****ociated
muscle cramps with cyclobenzaprine: A
retrospective review"...
- by chemotherapy.
These experimental procedures are not
standard care.
Vismodegib and
sonidegib are
drugs approved for
specially treating BCC, but are expensive...
-
target of the
natural teratogen cyclopamine. It also is the
target of
vismodegib, the
first hedgehog pathway inhibitor to be
approved by the U.S. Food...
- ISSN 1476-4598. PMC 4249599. PMID 25098767.
Clinical trial number NCT01154452 for "
Vismodegib and Gamma-Secretase/Notch
Signalling Pathway Inhibitor RO4929097 in Treating...
- from
cyclopamine and
vismodegib.
Itraconazole (ITZ)
inhibits SMO in the
presence of
mutations conferring resistance to
vismodegib and
other cyclopamine-competitive...
- palbociclib,
ribociclib -degib
hedgehog signaling pathway inhibitors vismodegib,
sonidegib -denib IDH1 and IDH2
inhibitors enasidenib,
ivosidenib -lisib...
