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Vidarabine or 9-β-D-arabinofuranosyladenine (ara-A) is an
antiviral drug
which is
active against herpes simplex and
varicella zoster viruses. Vidarabine...
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which also
produces vidarabine using the same gene cluster. The gene
cluster encodes completely separate pathways for
vidarabine and
pentostatin synthesis...
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another notch and led to
vidarabine vs.
aciclovir trials in the late 1980s. The
lower toxicity and ease of
administration over
vidarabine has led to aciclovir...
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Vidarabine phosphate is an
adenosine monophosphate nucleotide in
which ribose is
replaces by an
arabinso moiety. It has
antiviral and
possibly antineoplastic...
-
inspired the
discovery and
development of the
synthetic pharmaceutical drugs vidarabine,
which is used as an
antiviral drug, and
cytarabine which is used in the...
- famciclovir,
valaciclovir for the shingles, zoster-immune
globulin (ZIG), and
vidarabine.
Acyclovir is
frequently used as the drug of
choice in
primary VZV infections...
- β-D-ribofuranose. They are used as
cytostatics or virostatics.
Cytarabine Vidarabine Nelarabine Fludarabine Clofarabine Sorivudine Clevudine Cohen, Seymour...
- (CMV)
Vicriviroc HIV-1 Schering-Plough
pyrimidine CCR5
entry inhibitor Vidarabine Herpes Simplex,
Varicella Zoster Zalcitabine HIV
Zanamivir (Relenza) Influenza...
- anticoagulants, such as
warfarin (reported rarely, but is
serious when it occurs)
Vidarabine Chlorpropamide Phenytoin Theophylline Cyclophosphamide, doxorubicin, bleomycin...
-
morbidity and
mortality are due to the use of
antiviral treatments such as
vidarabine and acyclovir. However,
morbidity and
mortality still remain high due...