-
Versican is a
large extracellular matrix proteoglycan that is
present in a
variety of
human tissues. It is
encoded by the VCAN gene.
Versican is a large...
-
antagonizing the
function of
three microRNAs - miR-216, miR-330 and miR-608. The
versican 3'UTR has been
shown to
regulate expression of the
matrix protein fibronectin...
- brevican, neurocan,
versican, aggrecan, phosphacan, hyaluronan, tenascin-R and
various link proteins. The
CSPGs aggrecan,
versican, neurocan, brevican...
- (CSPGs)
chondroitin sulfate bikunin, 25 kDa neurocan, 136 kDa
versican, 260–370 kDa,
present in many
adult tissues including blood vessels and...
- are
varied and have very
specific locations. For example, hyaluronan,
versican and
decorin are
present throughout the
dermis and
epidermis extracellular...
- is induced. Neurocan, brevican, and
versican levels are up-regulated one day post injury, and
neurocan and
versican remain elevated 4 w****s post injury...
-
procollagens and von
Willebrand factor as well as
cleavage of aggrecan,
versican,
brevican and neurocan,
making them key
remodeling enzymes of the extracellular...
- CS/DS
Decorin Biglycan Versican HS/CS
Testican Perlecan CS
Chondroitin sulfate proteoglycans:
Aggrecan Neurocan Brevican CD44 CSPG4 CSPG5
Platelet factor...
- No
Total protein content 280–1360 μg/cm3 No
Hyaluronan 42–400 μg/cm3 No
Versican 60 μg/cm3 No
Collagen 300 μg/mL No
Albumin 293 ± 18 μg/cm3 No Immunoglobulin...
- CS/DS
Decorin Biglycan Versican HS/CS
Testican Perlecan CS
Chondroitin sulfate proteoglycans:
Aggrecan Neurocan Brevican CD44 CSPG4 CSPG5
Platelet factor...