- ac****ulation of
VLCFAs.
Enzymes that
produce VLCFAs are the
targets of
herbicides including pyroxasulfone. Some of the more
common saturated VLCFAs: lignoceric...
-
synthetic pathways than
those VLCFAs. The
first step of the
biosynthesis pathway for the
formation of
cuticular VLCFAs,
occurs with the de novo biosynthesis...
-
understood how they can have an ABCD1 gene
variant and
possess elevated VLCFAs and not
exhibit either Cerebral ALD,
Adrenal Insufficiency, or Adrenomyeloneuropathy...
- long
chain fatty acids (
VLCFAs),
which are
elevated in ALD. It does so by
competitively inhibiting the
enzyme that
forms VLCFAs. Lorenzo's oil, in combination...
-
chain fatty acids, some very long
chain fatty acids (
VLCFAs) are also known. Some of
these VLCFAs are also of the odd-chain variety. The most
common OCFA...
- of very long
chain fatty acids (
VLCFAs).
Defective function of the ACOX1
enzyme prevents proper breakdown of
VLCFAs,
leading to its ac****ulation and...
-
fatty acids (
VLCFAs) to
peroxisomes for degradation.
Patients with a
dysfunctional ABCD1 gene lack a
functional ALD protein,
causing VLCFAs to improperly...
-
fatty acids (
VLCFA) has not been
shown to
reduce blood VLCFA levels,
likely because humans can
endogenously produce most
VLCFA.
Plasma VLCFA levels are...
-
levels of
VLCFA ac****ulate in
various body
tissues and fluids. This
increased concentration then
incorporates into
various complex lipids where VLCFAs are not...
- acid with
aliphatic tails of 13 to 21
carbons Very long
chain fatty acid (
VLCFA),
fatty acid with
aliphatic tails of 22 or more
carbons Odd-chain fatty...
