- or gene
therapy does not
immediately normalize the
VLCFA levels in body tissues. The
levels of
VLCFA can be
normalized by
treatment with Lorenzo's oil...
- very-long-chain
fatty acid (
VLCFA) is a
fatty acid with 22 or more carbons.
Their biosynthesis occurs in the
endoplasmic reticulum.
VLCFA's can
represent up to...
-
fatty acids (
VLCFA) has not been
shown to
reduce blood VLCFA levels,
likely because humans can
endogenously produce most
VLCFA.
Plasma VLCFA levels are...
- acid with
aliphatic tails of 13 to 21
carbons Very long
chain fatty acid (
VLCFA),
fatty acid with
aliphatic tails of 22 or more
carbons Odd-chain fatty...
-
acids (
VLCFAs), such as aldehydes, alcohols, alkanes, ketones, and esters. Also
present are
other compounds in
cuticular wax
which are not
VLCFA derivatives...
- long
chain fatty acids (
VLCFAs),
which are
elevated in ALD. It does so by
competitively inhibiting the
enzyme that
forms VLCFAs. Lorenzo's oil, in combination...
-
levels of
VLCFA ac****ulate in
various body
tissues and fluids. This
increased concentration then
incorporates into
various complex lipids where VLCFAs are not...
-
chain fatty acids, some very long
chain fatty acids (
VLCFAs) are also known. Some of
these VLCFAs are also of the odd-chain variety. The most
common OCFA...
- single-bonded. It is
classified in the sub-group of very long
chain fatty acids (
VLCFA),
which includes molecules containing more than 20
carbon atoms. It has...
- long, 28 or more carbons, i.e. the very long
chain fatty acids (
VLCFA).
These VLCFA targets need not be free
fatty acids but also can be
acylated in...