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Uroporphyrinogens are
cyclic tetrapyrroles with four
propionic acid
groups ("P" groups) and four
acetic acid
groups ("A" groups).
There are four forms...
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Uroporphyrinogen III is a tetrapyrrole, the
first macrocyclic intermediate in the
biosynthesis of heme, chlorophyll,
vitamin B12, and siroheme. It is a...
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levels of
exposure to sunlight. The
primary cause is a
deficiency of
uroporphyrinogen decarboxylase (UROD), a
cytosolic enzyme that is a step in the enzymatic...
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Uroporphyrinogen I is an
isomer of
uroporphyrinogen III, a
metabolic intermediate in the
biosynthesis of heme. A type of
porphyria is
caused by production...
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Uroporphyrinogen III
synthase (EC 4.2.1.75) is an
enzyme involved in the
metabolism of the
cyclic tetrapyrrole compound porphyrin. It is
involved in the...
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metabolic disorder affecting heme,
caused by
deficiency of the
enzyme uroporphyrinogen cosynthetase. It is
extremely rare, with a
prevalence estimated at...
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Uroporphyrinogen III
decarboxylase (
uroporphyrinogen decarboxylase, or UROD) is an
enzyme (EC 4.1.1.37) that in
humans is
encoded by the UROD gene. Uroporphyrinogen...
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bilane (HMB),
which is
hydrolysed to form the
circular tetrapyrrole uroporphyrinogen III. This
molecule undergoes a
number of
further modifications. Intermediates...
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Uroporphyrinogen-III C-methyltransferase (EC 2.1.1.107),
uroporphyrinogen methyltransferase,
uroporphyrinogen-III methyltransferase, adenosylmethionine-uroporphyrinogen...
- B12. Many
steps are
involved in
converting aminolevulinic acid via
uroporphyrinogen III and
adenosylcobyric acid to the
final forms in
which it is used...
