Definition of Uronium. Meaning of Uronium. Synonyms of Uronium

- combined with strong acids, it undergoes protonation at oxygen to form uronium salts. It is also a Lewis base, forming metal complexes of the type [M(urea)6]n+...
- HATU (Hexafluorophosphate Azabenzotriazole Tetramethyl Uronium) is a reagent used in peptide coupling chemistry to generate an active ester from a carboxylic...
- HBTU (Hexafluorophosphate Benzotriazole Tetramethyl Uronium) is a coupling reagent used in solid phase peptide synthesis. It was introduced in 1978 and...
- basic conditions. It can exist in an N-form (guanidinium) or an O-form (uronium), but the N-form is generally considered to be more stable for this class...
- by-product formed in amide bond forming reactions and peptide synthesis with uronium and guanadinium-based reagents such as HATU, HBTU ad TCFH. Tetramethylurea...
- Bienert, Michael (1 February 2002). "The Uronium/Guanidinium Peptide Coupling Reagents: Finally the True Uronium Salts". Angewandte Chemie International...
- marketed as a safer and more effective replacement for benzotriazole-based uronium coupling reagents; see Peptide synthesis#Triazoles. This disambiguation...
- salt exchange. TCFH itself is a common reagent used in the preparation of uronium and guanidinium salts used for amide bond formation and peptide synthesis...
- coupling reagent COMU which is readily soluble as a dimethylmorpholine-uronium salt and which, like Oxyma, is superior to the standard additive HOBt for...
- first used to prepare pyrithione. The analogous thiourea approach via a uronium salt was reported in 1958 and provides a more convenient route to 2-mercaptopyridine...