- from
instructions in the DNA of the cell, and they can be increased, or
upregulated, when the
signal is weak, or decreased, or downregulated, when it is...
-
believed to be
involved in
skeletal muscle and
glucose metabolism. It is
upregulated in
response to exercise, and is
considered an
exercise mimetic. MOTS-c...
- conditions, GDF15 is
expressed in low
concentrations in most
organs and
upregulated because of
injury of
organs such as liver, kidney,
heart and lung. The...
- The p53
upregulated modulator of
apoptosis (PUMA) also
known as Bcl-2-binding
component 3 (BBC3), is a pro-apoptotic protein,
member of the Bcl-2 protein...
- Key
Features A 167
Upregulated in
several human cancers.
Crosslinks directly to
cellular mRNA.
Contains PCI domain. B 92
Upregulated in
several cancers...
- In humans,
cathepsin B is
encoded by the CTSB gene.
Cathepsin B is
upregulated in
certain cancers, in pre-malignant lesions, and in
various other pathological...
-
conserved in
eukaryotic cells that
downregulates protein synthesis and
upregulates specific genes in
response to
internal or
environmental stresses. The...
-
Although it
promotes the
elimination of virus-infected cells, it also
upregulates the
expression of ACE-2,
thereby facilitating the SARS-Cov2
virus to...
-
clavulanic acid
shows off-target
activity in the
nervous system by
upregulating the
glutamate transporter 1 (GLT-1) and has been
studied in the potential...
- responses. CTLA-4 is
constitutively expressed in
regulatory T
cells but only
upregulated in
conventional T
cells after activation – a
phenomenon which is particularly...