-
ubiquitin to a
substrate protein is
called ubiquitylation (or
ubiquitination or ubiquitinylation).
Ubiquitylation affects proteins in many ways: it can mark...
-
ubiquitination to
specific substrate proteins.[citation needed] The
ubiquitylation reaction proceeds in
three or four
steps depending on the mechanism...
-
recruitment and
summoning of the IKK (IkB kinase), TAK1, by
several ubiquitylation enzymes also ****ociated with the CARMA1/BCL10/MALT1 complex. MALT1 itself...
-
hydroxylates the
proline at the 564
position of HIF-1 alpha,
which allows ubiquitylation by the von Hippel-Lindau
tumor suppressor (pVHL) and
subsequent targeting...
-
glycosylation 2844
Amidation 1619
Hydroxylation 1523
Methylation 1133 O-linked
glycosylation 878
Ubiquitylation 826
Pyrrolidone carboxylic acid 504 Sulfation...
-
ubiquitin and
subsequent ubiquitin binding to E1.
Schematic diagram of the
ubiquitylation system. The
following genes encode ubiquitin-activating enzymes: UBA1...
-
highly modified.
These modifications include acetylation, methylation,
ubiquitylation, phosphorylation, sumoylation,
ribosylation and citrullination. Acetylation...
- cis-imidazoline
analog nutlin.
Levels and
stability of Mdm2 are also
modulated by
ubiquitylation. Mdm2 auto
ubiquitylates itself,
which allows for its
degradation by...
- to a
lysine residue on the
target protein.
Schematic diagram of the
ubiquitylation system. A
particular cell
usually contains only a few
types of E1 molecule...
- H.; Brockdorff, N. (2004). "Polycomb
Group Proteins Ring1A/B Link
Ubiquitylation of
Histone H2A to
Heritable Gene
Silencing and X Inactivation". Dev...
