-
necessary proteins for
homologous recombination repair.
Histones can be
ubiquitinated,
usually in the form of monoubiquitylation,
although polyubiquitylated...
- ubiquitination.
Cullin 3
ubiquitinates NRF2,
while Keap1 is a
substrate adaptor protein that
facilitates the reaction. Once NRF2 is
ubiquitinated, it is transported...
-
processing of
different kinds of
misfolded proteins (e.g.
ubiquitinated vs. non-
ubiquitinated proteins).
Segregation of
toxic protein aggregates into JUNQ...
- E6-****ociated protein,
which has
ubiquitin ligase activity, acts to
ubiquitinate p53,
leading to its
proteosomal degradation. E7 (in
oncogenic HPVs) acts...
- and the
resulting polyphosphorylated Akt is
ubiquitinated partly by E3
ligase NEDD4. Most of the
ubiquitinated-phosphorylated-Akt1 is
degraded by the proteasome...
- they can be
organized into one place.
Since Lewy
bodies are made of
ubiquitinated proteins that
would be
handled in the ubiquitin-proteasome pathway,...
-
recognized by
molecular chaperones and
become ubiquitinated by chaperone-****ociated
ubiquitin ligases. The
ubiquitinated proteins are
enclosed in autophagosomes...
-
large role in the
transport of
ubiquitinated proteins and
receptors to a lysosome.
ESCRT complexes transport ubiquitinated cargo to
cellular vesicles that...
-
accounting for lack of
ubiquitinated Lewy
bodies in parkin-mutant PD. Similarly,
native parkin reduces death of SH-SY5Y
neurons by
ubiquitinating other Lewy body...
- HECT domain, and
multiple amino acids that are
phosphorylated and
ubiquitinated. ITCH is
regulated by MAPK8. MAPK8
regulates JUNB
protein turnover by...
