-
Ubiquitin is a
small (8.6 kDa)
regulatory protein found in most
tissues of
eukaryotic organisms, i.e., it is
found ubiquitously. It was
discovered in...
-
Proteasomes are
protein complexes which degrade ubiquitin-tagged
proteins by proteolysis, a
chemical reaction that
breaks peptide bonds.
Enzymes that...
- A
ubiquitin ligase (also
called an E3
ubiquitin ligase) is a
protein that
recruits an E2
ubiquitin-conjugating
enzyme that has been
loaded with ubiquitin...
-
Ubiquitin-activating enzymes, also
known as E1 enzymes,
catalyze the
first step in the
ubiquitination reaction,
which (among
other things) can target...
-
Ubiquitin carboxy-terminal
hydrolase L1 (EC 3.1.2.15,
ubiquitin C-terminal hydrolase, UCH-L1) is a
deubiquitinating enzyme. UCH-L1 is a
member of a gene...
-
encoded by the UBC gene in humans. Polyubiquitin-C is one of the
sources of
ubiquitin,
along with UBB, UBA52, and RPS27A. UBC gene is one of the two stress-regulated...
-
Ubiquitin is a
protein that in
humans is
encoded by the UBB gene.
Ubiquitin is one of the most
conserved proteins known in
eukaryotic organisms. Ubiquitin...
-
Ubiquitin-conjugating enzymes, also
known as E2
enzymes and more
rarely as
ubiquitin-carrier enzymes,
perform the
second step in the
ubiquitination reaction...
-
ubiquitin proteases,
ubiquitin hydrolases, or
ubiquitin isopeptidases, are a
large group of
proteases that
cleave ubiquitin from proteins.
Ubiquitin is...
-
Ubiquitin-binding
domains (UBDs) are
protein domains that
recognise and bind non-covalently to
ubiquitin through protein-protein interactions. As of 2019...
