-
Ubiquitin is a
small (8.6 kDa)
regulatory protein found in most
tissues of
eukaryotic organisms, i.e., it is
found ubiquitously. It was
discovered in...
- A
ubiquitin ligase (also
called an E3
ubiquitin ligase) is a
protein that
recruits an E2
ubiquitin-conjugating
enzyme that has been
loaded with ubiquitin...
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Proteasomes are
protein complexes which degrade ubiquitin-tagged
proteins by proteolysis, a
chemical reaction that
breaks peptide bonds.
Enzymes that...
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Ubiquitin is a
protein that in
humans is
encoded by the UBB gene.
Ubiquitin is one of the most
conserved proteins known in
eukaryotic organisms. Ubiquitin...
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encoded by the UBC gene in humans. Polyubiquitin-C is one of the
sources of
ubiquitin,
along with UBB, UBA52, and RPS27A. UBC gene is one of the two stress-regulated...
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Ubiquitin carboxy-terminal
hydrolase L1 (EC 3.1.2.15,
ubiquitin C-terminal hydrolase, UCH-L1) is a
deubiquitinating enzyme. UCH-L1 is a
member of a gene...
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Ubiquitin D is a
protein that in
humans is
encoded by the UBD gene, also
known as FAT10. UBD acts like
ubiquitin, by
covalently modifying proteins and...
- enzymology, an
ubiquitin-calmodulin
ligase (EC 6.3.2.21) is an
enzyme that
catalyzes the
chemical reaction n ATP +
calmodulin + n
ubiquitin ⇌ {\displaystyle...
-
Linear ubiquitin chain ****embly
complex (LUBAC) is a multi-protein
complex and the only
known E3
ubiquitin ligase able to
conjugate ubiquitin in a head-to-tail...
-
Ubiquitin-binding
domains (UBDs) are
protein domains that
recognise and bind non-covalently to
ubiquitin through protein-protein interactions. As of 2019...
