-
Trypanothione is an
unusual form of
glutathione containing two
molecules of
glutathione joined by a
spermidine (polyamine) linker. It is
found in parasitic...
- In enzymology, a
trypanothione synthase (EC 6.3.1.9) is an
enzyme that
catalyzes the
chemical reaction glutathione +
glutathionylspermidine + ATP ⇌ {\displaystyle...
- In enzymology, a
trypanothione-disulfide
reductase (EC 1.8.1.12) is an
enzyme that
catalyzes the
chemical reaction trypanothione + NADP+ ⇌ {\displaystyle...
-
reacts with
trypanothione (a spermidine-glutathione
adduct that
replaces glutathione in trypanosomes). It
forms a mel****n oxide-
trypanothione adduct (Mel...
- PMID 15012109.
Greig N;
Wyllie S;
Vickers TJ;
Fairlamb AH (2006). "
Trypanothione-dependent
glyoxalase I in
Trypanosoma cruzi".
Biochemical Journal. 400...
-
glutathione reduction is
performed by
either the
thioredoxin or the
trypanothione system, respectively.
Glutathione plays a key role in
maintaining proper...
- an
enzyme in more than one way. For example, in the
figure showing trypanothione reductase from the
human protozoan parasite Trypanosoma cruzi, two molecules...
- the Actinomycetes,
bacillithiol in some gram-positive bacteria, or by
trypanothione in the Kinetoplastids.
Vitamin E is the
collective name for a set of...
- parasites, and
named it
trypanothione. This
thiol metabolite is
quite different from its
human equivalent, glutathione.
Trypanothione allows the parasites...
- chaperones : Hsp90 and cyclophilin ; and, On
trypanosomal enzymes :
trypanothione and
glutationylspermidine synthetases (1995)
Doctoral advisor Christopher...
