- A
trinucleotide repeat expansion, also
known as a
triplet repeat expansion, is the DNA
mutation responsible for
causing any type of
disorder categorized...
- In genetics,
trinucleotide repeat disorders, a
subset of
microsatellite expansion diseases (also
known as
repeat expansion disorders), are a set of over...
- (Htt).
Expansion of CAG
repeats of cytosine-adenine-guanine (known as a
trinucleotide repeat expansion) in the gene
coding for the
huntingtin protein results...
-
repetitive DNA sequences. It is a form of
mutation that
leads to
either a
trinucleotide or
dinucleotide expansion, or
sometimes contraction,
during DNA replication...
-
dinucleotide repeats (two
repeating nucleotides e.g. A-C-A-C-A-C...) and
trinucleotide repeats. Long
repeats include repeats of
entire genes. This classification...
- in the
severity of
symptoms is also noted. Anti****tion is
common in
trinucleotide repeat disorders, such as Huntington's
disease and
myotonic dystrophy...
- (CTG)
triplet repeats,
termed trinucleotide repeat expansion and
classifying DM1 as one of
several trinucleotide repeat disorders. This
expansion occurs...
-
demonstrate one of the most
commonly observed manifestations of this process.
Trinucleotide repeat disorders also
follow a non-Mendelian
pattern of inheritance...
- on the X chromosome, most
commonly an
increase in the
number of CGG
trinucleotide repeats in the 5'
untranslated region of FMR1.
Mutation at that site...
-
particular mutation of the
androgen receptor's
polyglutamine tract called a
trinucleotide repeat expansion. SBMA
results when the
length of the polyglutamine...
