-
nuclear RNAs
contain unique 5′-caps. Sm-class
snRNAs are
found with 5′-
trimethylguanosine caps,
while Lsm-class
snRNAs are
found with 5′-monomethylphosphate...
- stem-loop structure, as well as
hypermethylation of the 5′ cap to form
trimethylguanosine. The 3′ stem
structure is
necessary for
recognition by the survival...
-
Trimethylguanosine synthase is an
enzyme that in
humans is
encoded by the TGS1 gene. TGS1 has been
shown to
interact with: CREB-binding protein, and EED...
-
modified to a 7-methylguanosine cap) is hyper-methylated to 2,2,7-
trimethylguanosine and the
other (3') end of the
snRNA is trimmed. This modification...
-
several nematode species.
These sRNAs contain a
characteristic 2,2,7-
trimethylguanosine (TMG) cap
structure that
identifies them as non-coding RNAs that have...
- non-coding RNA
transcripts in C. elegans. A
systematic survey of 2,2,7-
trimethylguanosine (TMG) 5′
capped transcripts in C.elegans
using anti TMG antibodies...
-
similar to that of U RNAs
Features shared by all
HSURs include: 5′-
trimethylguanosine caps 3′
terminal stem-loops
canonical Sm protein-binding site (AUUUUUG)...
-
isoforms of PRIP-interacting
protein with
methyltransferase domain/
trimethylguanosine synthase localizes to the
cytoplasm and nucleus". Biochem. Biophys...
- processed. TGS-1
hypermethylation the 5'-methylguanosine cap to an N2,2,7
trimethylguanosine (TMG) cap,
which inhibits hTR maturation.
Binding of the Dyskerin...
-
localization signal. The
latter is
composed of the 5'-2,2,7-terminal
trimethylguanosine (m3G) cap
structure of the U
snRNA and the Sm core domain. The protein...
