-
substituents attached to
adjacent ring carbons.
These substitute groups are
trifluoromethylated 1-phenylethanol and
fluorophenyl group.
Aprepitant also has a third...
-
known as 4-amino-2-(trifluoromethyl)benzonitrile, is a
cyanated and
trifluoromethylated derivative of aniline. It is the
starting material in one of the...
- that
introduces a
trifluoromethyl group in an
organic compound.
Trifluoromethylated compounds are of some
importance in
pharmaceutical industry and agrochemicals...
-
Bendroflumethiazide Holdrege CT,
Babel RB,
Cheney LC (1959). "Synthesis of
Trifluoromethylated Compounds Possessing Diuretic Activity1".
Journal of the American...
- It is a
precursor to trifluoromethyltrimethylsilane, a po****r
trifluoromethylating reagent in
organic synthesis.
Alternatives for
normally occupied...
- Trifluoroacetaldehyde: A
useful industrial bulk
material for the
synthesis of
trifluoromethylated amino compounds,
Hideyuki Mimura,
Kosuke Kawada,
Tetsuya Yama****a...
- PMC 2547140. PMID 17900144. Browne,
Duncan L. (3
February 2014). "The
Trifluoromethylating Sandmeyer Reaction: A
Method for
Transforming C–N into C–CF". Angewandte...
- de
Almeida G,
Bevan CL,
Jiang W, et al. (September 2018). "Novel
Trifluoromethylated Enobosarm Analogues with
Potent Antiandrogenic Activity In Vitro...
-
operates via a free
radical mechanism. This
reagent is also able to
trifluoromethylate electron-deficient
aromatic compounds under biphasic conditions. Zinc...
- active) α,α-difluoro-γ-lactams and has been used in the
synthesis of
trifluoromethylated C-nucleosides.
Acetyl chloride Trifluoroacetic acid Nagashima, H...
