- to a template,
cells use an error-prone
recovery mechanism known as
translesion synthesis as a last resort.
Damage to DNA
alters the
spatial configuration...
-
synthesizing past the
damaged site. However, in
translesion synthesis, the CPD is byp****ed by
translesion polymerases, and
replication and or transcription...
-
replication process, such as
polymerization of DNA or RNA,
terminal transfer,
translesion synthesis (TLS), non-homologous end
joining (NHEJ), and
possibly in restarting...
-
appropriate repair pathway.
Another function of Pol IV is to
perform translesion synthesis at the
stalled replication fork like, for example, byp****ing...
- Biology: A DNA
polymerase found in
higher eukaryotes and
implicated in
translesion synthesis. Chemistry: The
stoichiometric coefficient. Psychology: The...
-
polymerase eta is a
eukaryotic DNA
polymerase involved in the DNA
repair by
translesion synthesis. The gene
encoding DNA
polymerase eta is POLH, also
known as...
-
during other forms of repair, or
cause an
error during replication (
translesion synthesis).
Mutations may also
result from substitution,
insertion or...
- post-replication
repair (PRR). In PRR,
there are two sub-pathways: (1) a
translesion synthesis pathway,
which is
carried out by
specialised DNA polymerases...
-
endogenously caused damages may be
converted into
mutations by
inaccurate translesion synthesis or
inaccurate DNA
repair (e.g. by non-homologous end joining)...
- of DNA Polymerases,
which are
capable of
performing DNA
translesion synthesis (TLS).
Translesion polymerases byp**** DNA
damage lesions during DNA replication...
