-
AICAR transformylase. PurN GAR
transformylase is
found in
eukaryotes and prokaryotes. However, a
second GAR
transformylase, PurT GAR
transformylase has...
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formyltransferase (EC 2.1.2.2), also
known as
glycinamide ribonucleotide transformylase (GAR Tfase), is an
enzyme with
systematic name 10-formyltetrahydrof...
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formyltransferase (EC 2.1.2.3), also
known by the
shorter name
AICAR transformylase, is an
enzyme that
catalyzes the
chemical reaction 10-formyltetrahydrofolate...
-
molecularly cloned human 5-aminoimidazole-4-carboxamide
ribonucleotide transformylase". J Biochem. 122 (2): 309–13. doi:10.1093/oxfordjournals.jbchem.a021754...
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Redfield BG,
Weissbach H (1967). "Methionyl
soluble ribonucleic acid
transformylase. I.
Purification and
partial characterization". J. Biol. Chem. 242 (7):...
-
structures of a
chemotherapeutic target:
human glycinamide ribonucleotide transformylase". Biochemistry. 44 (29): 9841–50. doi:10.1021/bi050307g. PMID 16026156...
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activated glycine onto PRPP,
forming glycineamide ribonucleotide (GAR). GAR
transformylase adds a
formyl group onto the
amino group of GAR,
forming formylglycinamide...
- The N
domain is very
similar to that of
glycinamide ribonucleotide transformylase.
Although the
orientation of the B
domains varies, the
structure of...
-
ribonucleotide (GAR). Co-enzyme N10-formyl-THF,
along with
enzyme GAR
transformylase, then
donates a one-carbon unit to the
amino group onto the glycine...
- (1991). "Multisubstrate
Adduct Inhibitors of
Glycinamide Ribonucleotide Transformylase:
Synthetic and
Enzyme Generated". Tetrahedron. 47 (14–15): 2351–2364...
