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Transcobalamins are
carrier proteins which bind
cobalamin (B12).
Transcobalamin I (TC-1), also
known as
haptocorrin (HC), R-factor, and R-protein is encoded...
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circulating B12,
rendering it
unavailable for
cellular delivery by
transcobalamin II. This is
conjectured to be a
circulating storage function. Several...
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intrinsic factor protein is
encoded by the
CBLIF gene.
Haptocorrin (
transcobalamin I) is
another glycoprotein secreted by the
salivary glands which binds...
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Haptocorrin (HC) also
known as
transcobalamin-1 (TC-1) or
cobalophilin is a
transcobalamin protein that in
humans is
encoded by the TCN1 gene. One essential...
-
three different protein molecules: haptocorrin,
intrinsic factor and
transcobalamin II.
Methylcobalamin Hydroxocobalamin Adenosylcobalamin Cobalamin biosynthesis...
- adenosylcobalamin.
Cobalamins circulate bound to
serum proteins called transcobalamins (TC) and haptocorrins.
Hydroxocobalamin has a
higher affinity to the...
- stomach,
bound to a
glycoprotein secreted by the
salivary glands –
transcobalamin I also
called haptocorrin,
which protects the acid-sensitive vitamin...
- to both
transcobalamins. Most of the time, 80–94% of
vitamin B12 in the
blood binds to haptocorrin,
while only 6–20% is
binds to
transcobalamin ll. Only...
- humans,
dietary sources of
cobalamin are
bound after ingestion as
transcobalamins and
converted to the
coenzyme forms in
which they are used. Cobalamin...
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treat heartburn, and
metformin to
treat diabetes. A
genetic disorder,
transcobalamin II deficiency, or Imerslund–Gräsbeck
syndrome can be a cause. Nitrous...
