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Transcobalamins are
carrier proteins which bind
cobalamin (B12).
Transcobalamin I (TC-1), also
known as
haptocorrin (HC), R-factor, and R-protein is encoded...
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Haptocorrin (HC) also
known as
transcobalamin-1 (TC-1) or
cobalophilin is a
transcobalamin protein that in
humans is
encoded by the TCN1 gene. One essential...
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intrinsic factor protein is
encoded by the
CBLIF gene.
Haptocorrin (
transcobalamin I) is
another glycoprotein secreted by the
salivary glands which binds...
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circulating B12,
rendering it
unavailable for
cellular delivery by
transcobalamin II. This is
conjectured to be a
circulating storage function. Several...
- deficiency". Orphanet.
Retrieved 2024-05-15. "Methylmalonic
aciduria due to
transcobalamin receptor defect". Orphanet.
Retrieved 2024-04-27. "Methylmalonic acidemia...
-
three different protein molecules: haptocorrin,
intrinsic factor and
transcobalamin II.
Methylcobalamin Hydroxocobalamin Adenosylcobalamin Cobalamin biosynthesis...
- stomach,
bound to a
glycoprotein secreted by the
salivary glands –
transcobalamin I also
called haptocorrin,
which protects the acid-sensitive vitamin...
- to both
transcobalamins. Most of the time, 80–94% of
vitamin B12 in the
blood binds to haptocorrin,
while only 6–20% is
binds to
transcobalamin ll. Only...
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cases of
deficiency where myeloproliferative disorders,
liver disease,
transcobalamin II, or
small intestinal bacterial overgrowth are present. Low levels...
- A. Hall and P. C. J. Rogers; Hall, C. A.; Rogers, P. C. J. (1991). "
Transcobalamin II deficiency: Case
report and
review of the literature".
European Journal...
