- In the
context of gene regulation:
transactivation is the
increased rate of gene
expression triggered either by
biological processes or by
artificial means...
- to
human ER).[citation needed] The N-terminal A/B
domain is able to
transactivate gene
transcription in the
absence of
bound ligand (e.g., the estrogen...
-
transcription factor's
binding site.
Estrogen receptor (ER) has been
shown to
transactivate other transcription factors in this manner,
despite the
absence of an...
-
molecules simultaneously bind
multiple procaspases. The
procaspases transactivate via cleavage,
activate additional caspases in the cascade, and cleave...
- (SHBG).
Emerging evidence shows that some
phytoestrogens bind to and
transactivate peroxisome proliferator-activated
receptors (PPARs). In
vitro studies...
-
hyperlocomotion in
amphetamine treated rats.
Dopamine receptors can also
transactivate Receptor tyrosine kinases. Beta
Arrestin recruitment is
mediated by...
-
transcription factors such as NF-κB or AP-1
themselves are able to
transactivate target genes.
However activated GR can
complex with
these other transcription...
-
retinoblastoma protein (pRb) binding,
freeing the
transcription factor E2F to
transactivate its targets, thus
pushing the cell
cycle forward. All HPV can induce...
-
acetylcholine receptor Isoflavones genistein and
daidzein bind to and
transactivate all
three PPAR isoforms, α, δ, and γ. For example, membrane-bound PPARγ-binding...
-
ovarian cancer cell
motility by
merging three signalling pathways to
transactivate EGFR".
British Journal of Pharmacology. (n/a) ((n/a)): 913–932. doi:10...
