- environment. In
order to
quantify toxic effects,
toxicokinetics can be
combined with toxicodynamics. Such
toxicokinetic-toxicodynamic (TKTD)
models are used in...
- A
latrotoxin is a high-molecular m****
neurotoxin found in the
venom of
spiders of the
genus Latrodectus (widow spiders) as well as at
least one species...
-
contain heavy metals (e.g., lead, nickel), pesticides, and bacteria.
Toxicokinetics describes how the body
handles the
toxin over time,
including absorption...
-
applicable for risk ****essment than
traditional modeling approaches.
While toxicokinetics describes the
changes in the
concentrations of a
toxicant over time...
- in
laboratory animals.
Although there is
limited information about toxicokinetics in humans,
observations in m****
poisonings and
experimental studies...
-
Cadmium is a
naturally occurring toxic metal with
common exposure in
industrial workplaces,
plant soils, and from smoking. Due to its low
permissible exposure...
- today, only
several studies were
carried out on the
biodistribution and
toxicokinetics of ciguatoxins, most of
which were
carried out in rats or in vitro....
- is
affected by the
toxicity of abrin.
Information dealing with the
toxicokinetics of
abrin is
limited and debated. Due to its
biochemical properties and...
-
Andersen ME,
Clewell HJ 3rd (2012). "Physiologically
based pharmacokinetic/
toxicokinetic modeling". Com****tional Toxicology.
Methods in
Molecular Biology. Vol...
- half-life of 20
minutes compared to 300
minutes for a
typical human (see §
Toxicokinetics). As a result, the
metabolic kinetics,
blood saturation point, and tolerance...