-
Toremifene, sold
under the
brand name
Fareston among others, is a
medication which is used in the
treatment of
advanced breast cancer in postmenopausal...
- hot flushes.
Ospemifene is an
analogous metabolite of
toremifene.
Unlike tamoxifen,
toremifene is not a rat hepatocarcinogen, and
therefore ospemifene...
- in 2001, and
reincorporated in
Delaware in 2003. The
company licensed toremifene from
Orion Corporation, and
licensed andarine,
enobosarm and prostarine...
- miproxifene,
miproxifene phosphate, nafoxidine, ospemifene, panomifene, and
toremifene. The
antiestrogen ethamoxytriphetol (MER-25) is also
closely related,...
-
metabolic pathways as the
related triphenylethylene SERMs tamoxifen and
toremifene. The
affinity of
clomifene for the ER
relative to
estradiol ranges from...
-
postmenopausal women.
Toremifene is a
similar SERM drug to tamoxifen, but is less
common and only
approved for
treatment of
metastatic cancer.
Toremifene is generally...
-
Selective estrogen receptor modulators,
including raloxifene,
tamoxifen and
toremifene are banned. Clomiphene, cyclofenil, fulvestrant, and all
other anti-estrogenic...
- deaminohydroxytoremifene),
raloxifene (Evista),
tamoxifen (Nolvadex), and
toremifene (Fareston; 4-chlorotamoxifen).
SERMs that are
currently under development...
-
other triphenylethylenes, such as clomifene, nafoxidine, ospemifene,
toremifene, and
numerous others.
Other SERMs, like raloxifene, are
structurally distinct...
- therapy.
Therapy options include those used in
localized cancer, plus
toremifene and fulvestrant,
often used in
combination with CDK4/6
inhibitors (palbociclib...
