- DNA
topoisomerases (or
topoisomerases) are
enzymes that
catalyze changes in the
topological state of DNA,
interconverting relaxed and
supercoiled forms...
-
Topoisomerase inhibitors are
chemical compounds that
block the
action of
topoisomerases,
which are
broken into two
broad subtypes: type I topoisomerases...
- Type II
topoisomerases are
topoisomerases that cut both
strands of the DNA
helix simultaneously in
order to
manage DNA
tangles and supercoils. They use...
-
Topoisomerase IV is one of two Type II
topoisomerases in bacteria, the
other being DNA gyrase. Like gyrase,
topoisomerase IV is able to p**** one double-strand...
- In
molecular biology Type I
topoisomerases are
enzymes that cut one of the two
strands of double-stranded DNA,
relax the strand, and
reanneal the strand...
- Anti-Scl-70 (also
called anti-
topoisomerase I
after the type I
topoisomerase target) is an anti-
topoisomerase antibody-type of anti-nuclear autoantibodies...
- DNA
topoisomerase 1 is an
enzyme that in
humans is
encoded by the TOP1 gene. It is a DNA
topoisomerase, an
enzyme that
catalyzes the
transient breaking...
- Anti-
topoisomerase antibodies (ATA) are
autoantibodies directed against topoisomerase and
found in
several diseases, most
importantly scleroderma. Diseases...
- DNA
topoisomerase 2-beta is an
enzyme that in
humans is
encoded by the TOP2B gene. This gene
encodes a DNA
topoisomerase, an
enzyme that
controls and alters...
-
simply gyrase, is an
enzyme within the
class of
topoisomerase and is a
subclass of Type II
topoisomerases that
reduces topological strain in an ATP dependent...
