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Tolerogenic dendritic cells (a. k. a. tol-DCs, tDCs, or DCregs) are
heterogenous pool of
dendritic cells with immuno-suppressive properties,
priming immune...
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Tolerogenic therapy aims to
induce immune tolerance where there is
pathological or
undesirable activation of the
normal immune response. This can occur...
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resident DCs. BTLA is a
crucial molecule for DCs
mediated Treg conversion.
Tolerogenic DCs
express FasL and
TRAIL to
directly induce apoptosis of responding...
- self-peptide Ep1.B
derived from
apolipoprotein E.
These are
primarily tolerogenic plasmacytoid dendritic cells. In mice, it has been
estimated that dendritic...
- B-cells and
other immune effector cells on to the
target tissue. The
ideal tolerogenic therapy would target the
specific T-cell
clones co-ordinating the autoimmune...
- system's
production of
inflammatory cytokines are
suppressed and more
tolerogenic regulatory T-cells are expressed. This is due to
vitamin D's influence...
- well as
other less well-characterized
cells that help
establish a
local tolerogenic environment. B
cells also
express CD22, a non-specific
inhibitor receptor...
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reduce the risk of
autoimmunity and, subsequently, type 1 diabetes.
Tolerogenic therapies,
which s**** to
induce immune tolerance to beta-cell antigens...
- Michelson,
Daniel A.; Mathis,
Diane (October 2022). "Thymic
mimetic cells:
tolerogenic masqueraders".
Trends in Immunology. 43 (10): 782–791. doi:10.1016/j...
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achieved in
rodent models. Recently,
evidence has been
obtained for a
tolerogenic effect of a
spleen transplant in
miniature swine.[citation needed] Also...
