-
Tolcapone, sold
under the
brand name Tasmar, is a
medication used to
treat Parkinson's
disease (PD). It is a selective,
potent and
reversible nitrocatechol-type...
- opicapone, and
tolcapone,
which are used in the
treatment of Parkinson's disease.
Entacapone and
opicapone are
peripherally selective, but
tolcapone significantly...
-
Marketed Entacapone (Comtan, Comtess, Stalevo)
Opicapone (Ongentys)
Tolcapone (Tasmar) Not
marketed Nebicapone (BIA 3-202)
Neluxicapone Nitecapone (OR-462)...
- and
tolcapone ... have been
demonstrated to
reduce the dose of L-DOPA
required and also
cause improvement in
clinical symptoms,
although tolcapone emerged...
-
tolcapone "orphan drug status" in
studies aiming at the
treatment of
transthyretin familial amyloidosis (ATTR). However, as of 2015[update]
tolcapone...
-
selective monoamine oxidase B (MAO-B) inhibitor; but see more below),
tolcapone (a centrally-acting catechol-O-methyltransferase (COMT) inhibitor), and...
- of the
sympathetic nervous system.[citation needed] Some drugs, like
tolcapone (a
central COMT-inhibitor),
raise the
levels of all the catecholamines...
- the CNS
penetrant specific catecholamine-O-methyltransferase
inhibitor Tolcapone. Furthermore,
episodic memory is
enhanced through AZD3480, a selective...
- and
tolcapone. The drug
shows peripheral selectivity and does not
significantly act in the brain. In
contrast to the
centrally penetrant tolcapone, nebicapone...
-
Centrally active catechol-O-methyltransferase
inhibitors (COMTIs) like
tolcapone,
which are
likewise dopaminergic agents, have been
studied in the treatment...
