-
Thromboxane is a
member of the
family of
lipids known as eicosanoids. The two
major thromboxanes are
thromboxane A2 and
thromboxane B2. The distinguishing...
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Thromboxane A2 (TXA2) is a type of
thromboxane that is
produced by
activated platelets during hemostasis and has
prothrombotic properties: it stimulates...
- The
thromboxane receptor (TP) also
known as the
prostanoid TP
receptor is a
protein that in
humans is
encoded by the TBXA2R gene, The
thromboxane receptor...
-
Thromboxane A
synthase 1 (EC 5.3.99.5, platelet,
cytochrome P450,
family 5,
subfamily A), also
known as TBXAS1, is a
cytochrome P450
enzyme that, in humans...
-
Thromboxane B2 (TXB2) is an
inactive metabolite/product of
thromboxane A2. It is
almost completely cleared in the urine. It
itself is not
involved in platelet...
-
thromboxanes is due to its
irreversible inactivation of the
cyclooxygenase (COX) enzyme.
Cyclooxygenase is
required for
prostaglandin and
thromboxane...
- a.k.a. PAR-1)
Vorapaxar (Zontivity)
Thromboxane inhibitors Thromboxane receptor antagonists Terutroban Thromboxane synthase inhibitors Prevention and treatment...
-
effective vasodilator. Prostacyclin's
interactions contrast with
those of
thromboxane (TXA2),
another eicosanoid. Both
molecules are
derived from arachidonic...
- 99.1) that is
responsible for
biosynthesis of prostanoids,
including thromboxane and
prostaglandins such as prostacyclin, from
arachidonic acid. A member...
- upon by:
prostacyclin synthase to
create prostacyclin thromboxane-A
synthase to
create thromboxane A2 and 12-(S)-hydroxy-5Z,8E,10E-heptadecatrienoic acid...
