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Thrombopoiesis is the
formation of
thrombocytes (blood platelets) in the bone marrow.
Thrombopoietin is the main
regulator of
thrombopoiesis. Thrombopoietin...
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necessary for
megakaryocyte proliferation and maturation, as well as for
thrombopoiesis. This
protein is the
ligand for MLP/C_MPL, the
product of myeloproliferative...
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McMillan R,
Aledort LM,
Conklin GT, et al. (October 2006). "AMG 531, a
thrombopoiesis-stimulating protein, for
chronic ITP". The New
England Journal of Medicine...
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hematopoietic progenitors with the bone
marrow vascular niche is
required for
thrombopoiesis". Nat Med. 10 (1): 64–71. doi:10.1038/nm973. PMID 14702636. S2CID 21760081...
- also
promotes angioprotective and
proaggregant action. It
stimulates thrombopoiesis and
their release from bone marrow.
Haemostatic action is due to activation...
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cells which are
granulocytes but with an
extramedullar maturation.
Thrombopoiesis is
haematopoiesis of
thrombocytes (platelets).
Between 1948 and 1950...
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products are
currently available:
Romiplostim (trade name Nplate) is a
thrombopoiesis stimulating Fc-peptide
fusion protein (peptibody) that is administered...
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developing blood cell
lines are available, like
erythropoiesis and
thrombopoiesis.
Granulopoiesis is
regulated by
humoral agents, like colony-stimulating...
- -blast 'precursor cell') is a
precursor cell to a promegakaryocyte.
During thrombopoiesis, the
promegakaryocyte matures into the form of a megakaryocyte. From...
- of
intracranial hemorrhage and
other bleeding complications.
Several thrombopoiesis-stimulating
therapies including eltrombopag and
romiplostim are being...
