Definition of Thiolactone. Meaning of Thiolactone. Synonyms of Thiolactone

- Thiolactones are a class of heterocyclic compounds in organic chemistry. They are analogs of the more common lactones in which an oxygen atom is replaced...
- Homocysteine thiolactone (HTL) is an organosulfur compound with the formula H2NCHC(O)SCH2CH2. It is the thiolactone (intramolecular thioester) of homocysteine...
- for methionine synthase. Homocysteine can cyclize to give homocysteine thiolactone, a five-membered heterocycle. Because of this "self-looping" reaction...
- intestine and carboxylesterase 1 in the liver to a likewise inactive thiolactone, which is then converted by CYP3A4 and CYP2B6, and to a minor extent...
- CYP2C19, CYP2C9, CYP2B6, and CYP3A. The thiophene ring is converted to a thiolactone, which undergoes ring-opening. The active metabolite has three sites...
- acid: a novel mucolytic agent of the class of homocysteine thiolactone derivatives". Il Farmaco; Edizione Scientifica. 41 (1): 69–79. PMID 3956722...
- A/B-corrin-ring closure was also achieved by converting the thiolactone-thiolactame intermediate HE-40u to thiolactone-thioiminoester HE-45u by S-methylation of the...
- protein for degradation. Oxidation of the sulfur atom in thioesters (thiolactones) is postulated in the bioactivation of the antithrombotic prodrugs ticlopidine...
- biological function is hydrolysis of the reactive electrophile homocysteine thiolactone. Another of its activities is metabolic inactivation of the glycopeptide...
- transcriptional quorum-sensing (QS) system activated by an autoinducing, thiolactone-containing cyclic peptide (AIP). Agr occurs in 4 allelic subtypes that...