- Tioguanine, also
known as
thioguanine or 6-
thioguanine (6-TG) or
tabloid is a
medication used to
treat acute myeloid leukemia (AML),
acute lymphocytic...
-
analogues subclass of
antimetabolites family of medications. It
works via 6-
thioguanine to
disrupt the
making of RNA and DNA by cells.
Azathioprine was first...
-
structure of
metabolic purines.
Nucleobase analogues Thiopurines such as
thioguanine are used to
treat acute leukemias and
remissions in
acute granulocytic...
-
ranitidine for
gastroesophageal reflux disorder,
mercaptopurine and
thioguanine for the
treatment of leukemia,
allopurinol for gout,
pyrimethamine for...
-
mouse BALB/c strain. 4T1
cells are
epithelial and are
resistant to 6-
thioguanine. In
preclinical research, 4T1
cells have been used to
study breast cancer...
- deoxythioguanosine. Some
mercaptopurine is
converted to
nucleotide derivatives of 6-
thioguanine (6-TG) by the
sequential actions of
inosinate (IMP)
dehydrogenase and...
-
bromodeoxyuridine (BrdU) and a cell
lacking HGPRT is
resistant to 6-
thioguanine (6-TG) and 8-azaguanine. Thus,
selection with one of the
latter two drugs...
- nelarabine, cladribine, clofarabine, and pentostatin. The
thiopurines include thioguanine and mercaptopurine. Anti-microtubule
agents are plant-derived chemicals...
- combinations:
vincristine cyclophosphamide cytarabine daunorubicin etoposide thioguanine mercaptopurine Central nervous system relapse is
treated with intrathecal...
- to
treat one or more
types of leukemia, include: 6-Mercaptopurine 6-
Thioguanine ****nic
trioxide Asparaginase Cladribine Clofarabine Cyclophosphamide...
