-
Thioflavins are
fluorescent dyes that are
available as at
least two compounds,
namely Thioflavin T and
Thioflavin S. Both are used for
histology staining...
-
Pittsburgh compound B (PiB) is a
radioactive analog of
thioflavin T,
which can be used in
positron emission tomography scans to
image beta-amyloid plaques...
- fluorescent.
Thioflavin T is
obtained by the
methylation of
dehydrothiotoluidine with
methanol in the
presence of
hydrochloric acid.
Thioflavin S results...
- and an
ability to
stain with
specific dyes, such as
Congo red,
thioflavin T or
thioflavin S. The term "cross-β" was
based on the
observation of two sets...
-
fluorimetry equipment.
Thioflavins are dyes used for
histology staining and
biophysical studies of
protein aggregation. For example,
thioflavin T is used in the...
- solanezumab.
Imaging compounds,
notably Pittsburgh compound B, (6-OH-BTA-1, a
thioflavin), can
selectively bind to
amyloid beta in
vitro and in vivo. This technique...
-
confocal microscopy,
Congo red can be used as a
stable fluorescent stain.
Thioflavin Klaus Hunger,
Peter Mischke,
Wolfgang Rieper,
Roderich Raue,
Klaus Kunde...
- light,
makes the
amyloid proteins appear apple-green on microscopy. Also,
thioflavin T
stain may be used. A
number of
imaging techniques such as a Nuclear...
- electron-withdrawing
moiety with
numerous applications in dyes such as
thioflavin. Some
drugs contain this group,
examples being riluzole and pramipexole...
-
McLellan ME,
Frosch MP,
Hyman BT, et al. (February 2002). "A
lipophilic thioflavin-T
derivative for
positron emission tomography (PET)
imaging of amyloid...