-
chemical synthesis of glycosides.
Typical leaving groups are halides,
thioalkyl groups, or imidates, but acetate, phosphate, and O-pentenyl
groups are...
-
substitution in the 6-membered ring to any
extent with alkyl, alkoxy, haloalkyl,
thioalkyl, alkylenedioxy, or
halide substituents; (iv) by
substitution at the 2-position...
-
albeit with weak
potency (Ki = 0.25–2.4 μM; IC50 = 0.27–1.1 μM). C7α
thioalkyl derivatives of
spironolactone like the 7α-thioethyl
analogue were found...
