- resistance,
which has
responded favorably to
thiazolidinediones.
There are some
indications that
thiazolidinediones provide some
degree of
protection against...
-
combination with
other oral
diabetic medications.[citation needed]
Thiazolidinediones (TZDs), also
known as "glitazones," bind to PPARγ,
peroxisome proliferator...
- Metformin, sold
under the
brand name Glucophage,
among others, is the main first-line
medication for the
treatment of type 2 diabetes,
particularly in...
- in turn
termed PPAR ligands. The best-known PPAR
ligands are the
thiazolidinediones.
After PPARδ (delta) was
identified in
humans in 1992, it
turned out...
-
Glycogen synthase kinase 3 (GSK-3) is a serine/threonine
protein kinase that
mediates the
addition of
phosphate molecules onto
serine and
threonine amino...
- in the
nucleus and
become activated by
ligands such as
thiazolidinediones.
Thiazolidinediones enter the cell, bind to the
nuclear receptors, and alter...
-
never used as a medication, but it
sparked interest in the
effects of
thiazolidinediones.
Several analogues were
later developed, some of which—such as pioglitazone...
- and anti-inflammatory drug, and a
member of the drug
class of the
thiazolidinediones. It was
prescribed for
people with
diabetes mellitus type 2. It was...
-
excessive fluid or salt intake, and
medication such as
NSAIDs and
thiazolidinediones.
NSAIDs increase the risk twofold. A
number of
medications may cause...
- in
patients with a
known hy****nsitivity to pioglitazone,
other thiazolidinediones or any of
components of its
pharmaceutical forms. It is ineffective...
