- resistance,
which has
responded favorably to
thiazolidinediones.
There are some
indications that
thiazolidinediones provide some
degree of
protection against...
- also
available in
combination with
other oral
diabetic medications.
Thiazolidinediones (TZDs), also
known as "glitazones," bind to PPARγ,
peroxisome proliferator...
- and anti-inflammatory drug, and a
member of the drug
class of the
thiazolidinediones. It was
prescribed for
people with
diabetes mellitus type 2. It was...
-
Glycogen synthase kinase 3 (GSK-3) is a serine/threonine
protein kinase that
mediates the
addition of
phosphate molecules onto
serine and
threonine amino...
- in the
nucleus and
become activated by
ligands such as
thiazolidinediones.
Thiazolidinediones enter the cell, bind to the
nuclear receptors, and alter...
- Metformin, sold
under the
brand name Glucophage,
among others, is the main first-line
medication for the
treatment of Type 2 diabetes,
particularly in...
-
excessive fluid or salt intake, and
medication such as
NSAIDs and
thiazolidinediones.
NSAIDs increase the risk twofold. A
number of
medications may cause...
-
never used as a medication, but it
sparked interest in the
effects of
thiazolidinediones.
Several analogues were
later developed, some of which—such as pioglitazone...
- (sitagliptin),
agents that make the body more
sensitive to
insulin (
thiazolidinedione) and
agents that
increase the
excretion of
glucose in the
urine (SGLT2...
-
effect on
cardiovascular risk. From 2001,
reports began to link the
thiazolidinediones (the
class of
drugs to
which rosiglitazone belongs) to
heart failure...
