- The
thiazolidinediones /θaɪ.əˌzoʊlɪdiːnˈdaɪ.oʊn/,
abbreviated as TZD, also
known as
glitazones after the
prototypical drug ciglitazone, are a
class of...
- Metformin, sold
under the
brand name Glucophage,
among others, is the main first-line
medication for the
treatment of type 2 diabetes,
particularly in...
- Use is not
recommended in
pregnancy or breastfeeding. It is in the
thiazolidinedione (TZD)
class and
works by
improving sensitivity of
tissues to insulin...
- It
contains pioglitazone, a
thiazolidinedione, and metformin, a biguanide.
Pioglitazone is a
member of the
thiazolidinedione class, it
decreases insulin...
-
combination with
other oral
diabetic medications.[citation needed]
Thiazolidinediones (TZDs), also
known as "glitazones," bind to PPARγ,
peroxisome proliferator...
- a
thiazolidinedione.
Developed by
Takeda Pharmaceuticals in the
early 1980s, it is
considered the
prototypical compound for the
thiazolidinedione class...
- (sitagliptin),
agents that make the body more
sensitive to
insulin (
thiazolidinedione) and
agents that
increase the
excretion of
glucose in the
urine (SGLT2...
-
Glycogen synthase kinase 3 (GSK-3) is a serine/threonine
protein kinase that
mediates the
addition of
phosphate molecules onto
serine and
threonine amino...
-
Rosiglitazone (trade name Avandia) is an
antidiabetic drug in the
thiazolidinedione class. It
works as an
insulin sensitizer, by
binding to the PPAR in...
- and anti-inflammatory drug, and a
member of the drug
class of the
thiazolidinediones. It was
prescribed for
people with
diabetes mellitus type 2. It was...
