- The
thiazolidinediones /θaɪ.əˌzoʊlɪdiːnˈdaɪ.oʊn/,
abbreviated as TZD, also
known as
glitazones after the
prototypical drug ciglitazone, are a
class of...
- and anti-inflammatory drug, and a
member of the drug
class of the
thiazolidinediones. It was
prescribed for
people with
diabetes mellitus type 2. It was...
- a
thiazolidinedione.
Developed by
Takeda Pharmaceuticals in the
early 1980s, it is
considered the
prototypical compound for the
thiazolidinedione class...
-
Rosiglitazone (trade name Avandia) is an
antidiabetic drug in the
thiazolidinedione class. It
works as an
insulin sensitizer, by
binding to the PPAR in...
- (sitagliptin),
agents that make the body more
sensitive to
insulin (
thiazolidinedione) and
agents that
increase the
excretion of
glucose in the
urine (SGLT2...
- Use is not
recommended in
pregnancy or breastfeeding. It is in the
thiazolidinedione (TZD)
class and
works by
improving sensitivity of
tissues to insulin...
-
Glycogen synthase kinase 3 (GSK-3) is a serine/threonine
protein kinase that
mediates the
addition of
phosphate molecules onto
serine and
threonine amino...
-
excessive fluid or salt intake, and
medication such as
NSAIDs and
thiazolidinediones.
NSAIDs increase the risk twofold. A
number of
medications may cause...
-
effect on
cardiovascular risk. From 2001,
reports began to link the
thiazolidinediones (the
class of
drugs to
which rosiglitazone belongs) to
heart failure...
-
limited their use.
Other classes of
medications include: sulfonylureas,
thiazolidinediones,
dipeptidyl peptidase-4 inhibitors, SGLT2 inhibitors, and GLP-1 receptor...
