Definition of Thapsigargin. Meaning of Thapsigargin. Synonyms of Thapsigargin

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Definition of Thapsigargin

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Meaning of Thapsigargin from wikipedia

- Thapsigargin is a non-competitive inhibitor of the sarco/endoplasmic reticulum Ca2+ ATPase (SERCA). Structurally, thapsigargin is classified as a guaianolide...
- active ingredient in G-202 is a chemotherapeutic agent derived from thapsigargin, a plant-based cytotoxin that kills by disrupting the calcium balance...
- § Structure) in vivo. This is effected by its inhibiting thrombin and thapsigargin, two activators of SOCE that increase intracellular free calcium. Phenolphthalein...
- organic synthesis is the expansion of the Wieland–Miescher ketone to thapsigargin: In this reaction, diastereoselective reduction of the ketone 1 with...
- garganica. The chemical compound thapsigargin has been isolated from Thapsia garganica. A synthetic prodrug of thapsigargin called "G-202" is in preliminary...
- 3166-1 country code TG) Torture Garden (fetish club), London, England Thapsigargin, a tumor promoter Thyroglobulin, a protein Transgenic, the transfer of...
- termed G202 consists of an analog of the highly toxic natural product thapsigargin coupled to a peptide recognized as a substrate by the protease Prostate-Specific...
- heart failure. For experimental purposes, SERCA can be inhibited by thapsigargin and induced by istaroxime. SERCA function is upregulated in the skeletal...
- Tyrosine kinase Testosterone Tetrahydrocannabinol (THC) Tetracycline Thapsigargin Thaumatin Thiamine (vitamin B1) – C12H17ClN4OS·HCl Threonine Thrombopoietin...
- drug designation as a treatment during chemotherapy for HCC. It is a thapsigargin-based prodrug with cytotoxic activity used to reduce blood flow to the...