Definition of Thapsigargin. Meaning of Thapsigargin. Synonyms of Thapsigargin

- Thapsigargin is a non-competitive inhibitor of the sarco/endoplasmic reticulum Ca2+ ATPase (SERCA). Structurally, thapsigargin is classified as a guaianolide...
- organic synthesis is the expansion of the Wieland–Miescher ketone to thapsigargin: In this reaction, diastereoselective reduction of the ketone 1 with...
- garganica. The chemical compound thapsigargin has been isolated from Thapsia garganica. A synthetic prodrug of thapsigargin called "G-202" is in preliminary...
- active ingredient in G-202 is a chemotherapeutic agent derived from thapsigargin, a plant-based cytotoxin that kills by disrupting the calcium balance...
- § Structure) in vivo. This is effected by its inhibiting thrombin and thapsigargin, two activators of SOCE that increase intracellular free calcium. Phenolphthalein...
- 3166-1 country code TG) Torture Garden (fetish club), London, England Thapsigargin, a tumor promoter Thyroglobulin, a protein Transgenic, the transfer of...
- CPA also binds to SERCA ATPase at the same site as another inhibitor, thapsigargin (TG). In this way, CPA lowers the ability of SERCA ATPase to bind an...
- termed G202 consists of an analog of the highly toxic natural product thapsigargin coupled to a peptide recognized as a substrate by the protease Prostate-Specific...
- structure and mechanism, and both are inhibited by the tumor-promoting agent thapsigargin, which does not affect the plasma membrane Ca2+ pumps. Active...
- drug designation as a treatment during chemotherapy for HCC. It is a thapsigargin-based prodrug with cytotoxic activity used to reduce blood flow to the...