-
Tezacaftor is a drug used for the
treatment of
cystic fibrosis (CF) in
people six
years and older, who have a F508del mutation, the most
common type of...
- Elexacaftor/
tezacaftor/ivacaftor, sold
under the
brand names Trikafta and Kaftrio, is a fixed-dose
combination medication used to
treat cystic fibrosis...
- in
combination medications, lumacaftor/ivacaftor,
tezacaftor/ivacaftor, and elexacaftor/
tezacaftor/ivacaftor
which are used to
treat people with cystic...
-
available in a
single pill with
ivacaftor and
tezacaftor; the fixed-dose combination, elexacaftor/
tezacaftor/ivacaftor (brand name Trikafta), is used to...
- 2017,
Vertex announced Phase 3 data from a dual
combination treatment,
tezacaftor plus ivacaftor, in
patients with
cystic fibrosis. On 12
February 2018...
- R07AX30
Ivacaftor and
lumacaftor R07AX31
Ivacaftor and
tezacaftor R07AX32 Ivacaftor,
tezacaftor and
elexacaftor "ATC (Anatomical
Therapeutic Chemical classification...
-
approved the
combination ivacaftor/
tezacaftor; the
manufacturer announced a list
price of $292,000 per year.
Tezacaftor helps move the CFTR
protein to the...
-
endometrial carcinoma Lenvatinib Eisai endometrial carcinoma Elexacaftor/
tezacaftor/ivacaftor
Vertex Pharmaceuticals cystic fibrosis Zanubrutinib BeiGene...
- CFTR
modulators for
specific mutations. One such drug is elexacaftor/
tezacaftor/ivacaftor. However, the cost of CFTR
modulators is high. In
addition to...
- (~ 50% of CF patients). Most recently, Grooten****s's team
discovered Tezacaftor (VX-661) and
Elexacaftor (VX-445),
which in
combination with Ivacaftor...