-
Tetrahydrodeoxycorticosterone (abbreviated as THDOC; 3α,21-dihydroxy-5α-pregnan-20-one), also
referred to as allotetrahydrocorticosterone, is an endogenous...
-
neurosteroids including allopregnanolone, androstanediol, and
tetrahydrodeoxycorticosterone.
Adverse effects from
finasteride are rare in men with already...
- for the
production of
neurosteroids like allopregnanolone,
tetrahydrodeoxycorticosterone (THDOC), and 3α-androstanediol from progesterone, deoxycorticosterone...
- 3α-hydroxy ring A-reduced
pregnane steroids allopregnanolone and
tetrahydrodeoxycorticosterone increase the GABA-mediated
chloride currents while pregnenolone...
-
synthesis of the
endogenous neurosteroids allopregnanolone,
tetrahydrodeoxycorticosterone, and 3α-androstanediol. It is also
known to
catalyze the reversible...
- function.
These neurosteroids,
which include allopregnanolone,
tetrahydrodeoxycorticosterone (THDOC), and 3α-androstanediol, act as
potent positive allosteric...
- neuroprotective, and
neurogenic effects.
Major examples include tetrahydrodeoxycorticosterone (THDOC), the
androstane 3α-androstanediol, the
cholestane cholesterol...
-
inhibitory neurosteroids such as allopregnanolone,
THDOCTooltip tetrahydrodeoxycorticosterone, and 3α-androstanediol, respectively. MPA has been described...
- 20-dione). The 21-hydroxylated
derivative of this compound,
tetrahydrodeoxycorticosterone, is an
endogenous inhibitory neurosteroid with
similar properties...
-
including allopregnanolone (from progesterone),
THDOCTooltip tetrahydrodeoxycorticosterone (from deoxycorticosterone), and 3α-androstanediol (from testosterone)...
