- gets its name from
homology with PTPs and
tensin 1. More
detailed structure comparisons have
revealed that
tensins 1-3, PTEN,
auxilin and
other proteins in...
-
Phosphatase and
tensin homolog (PTEN) is a
phosphatase in
humans and is
encoded by the PTEN gene.
Mutations of this gene are a step in the development...
-
Jujutsu (****anese: 柔術 jūjutsu, ****anese pronunciation: [dʑɯːʑɯtsɯ] or [dʑɯꜜːʑɯtsɯ] ), also
known as jiu-jitsu and ju-jitsu (both /dʒuːˈdʒɪtsuː/ joo-JITS-oo)...
- on 10q23.3, a
tumor suppressor gene
otherwise known as
phosphatase and
tensin homolog, that
results in
dysregulation of the mTOR
pathway leading to errors...
-
Tensin-1 is a
protein that in
humans is
encoded by the TNS1 gene. The
protein encoded by this gene
localizes to
focal adhesions,
regions of the plasma...
-
Crystallographic structure of
human phosphatase and
tensin homolog (PTEN). The
active site of the blue N-terminal
phosphatase domain is
shown in yellow...
- 1038/ncb1622. PMID 17643115. S2CID 27088360.
Mouneimne G,
Brugge JS (2007). "
Tensins: a new
switch in cell migration". Dev. Cell. 13 (3): 317–9. doi:10.1016/j...
- When p53
itself is mutated,
other mutations can survive.
Phosphatase and
tensin homolog (PTEN),
another tumor suppressor gene, is
itself lost or mutated...
- state. The PI3K/AKT
pathway has a
natural inhibitor called Phosphatase and
tensin homolog (PTEN)
whose function is to
limit proliferation in cells, helping...
-
cytoskeleton via
adapter proteins such as talin, α-actinin, filamin,
vinculin and
tensin. Many
other intracellular signalling proteins, such as
focal adhesion kinase...