- DNA
repair machinery.
Should non-homologous end
joining occur at the
telomeric ends,
chromosomal fusion would result. The T-loop is
maintained by several...
-
occur naturally near the ends of the chromosomes,
better known as the
telomeric regions, and in
transcriptional regulatory regions of
multiple genes,...
-
Telomeric repeat–containing RNA (TERRA) is a long non-coding RNA
transcribed from
telomeres -
repetitive nucleotide regions found on the ends of chromosomes...
-
Telomeric repeat-binding
factor 2 is a
protein that is
present at
telomeres throughout the cell cycle. It is also
known as TERF2, TRF2, and TRBF2, and...
-
Telomeric repeat-binding
factor 1 is a
protein that in
humans is
encoded by the TERF1 gene. The
human TERF1 gene is
located in the
chromosome 8 at 73...
- it was
shown in the late 2000s that
telomeric repeats may be
transcribed as
telomeric RNAs (TelRNAs) or
telomeric repeat-containing RNAs.
These ncRNAs...
- 1038/nature.2012.11520. S2CID 87341731. "Structure and ****ng of
human telomeric DNA". ndbserver.rutgers.edu.
Retrieved 18 May 2023.
Greider CW, Blackburn...
- as to
regulate telomerase activity. In
mammals and
other vertebrates,
telomeric DNA
consists of
repeating double-stranded 5'-TTAGGG-3' (G-strand) sequences...
-
contains 16 genes, with PLCXD1 as the
furthermost PAR1 gene at the
distal telomeric end and XG at the
boundary of PAR1 at the
centromeric end. PAR2 contains...
- investigation.
Telomeric double stranded breaks or
telomeric dysfunction is
generated by
exogenous agents or
replicative stress.
Telomeric dysfunctions...
