-
Telomerase, also
called terminal transferase, is a
ribonucleoprotein that adds a species-dependent
telomere repeat sequence to the 3' end of telomeres...
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Telomerase reverse transcriptase (abbreviated to TERT, or
hTERT in humans) is a
catalytic subunit of the
enzyme telomerase, which,
together with the telomerase...
- the
University of California,
Santa Cruz.
Greider discovered the
enzyme telomerase in 1984,
while she was a
graduate student of
Elizabeth Blackburn at the...
-
discovery of how
chromosomes are
protected by
telomeres and the
enzyme telomerase.
During DNA replication, DNA
polymerase cannot replicate the sequences...
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Telomerase RNA component, also
known as TR, TER or TERC, is an
ncRNA found in
eukaryotes that is a
component of
telomerase, the
enzyme used to
extend telomeres...
- Salk
Institute for
Biological Studies. In 1984,
Blackburn co-discovered
telomerase, the
enzyme that
replenishes the telomere, with
Carol W. Greider. For...
- to
activate telomerase more than any
other known compound yet discovered: 8.8-fold. This
exceeds the
activation by
other known telomerase activators:...
-
disorders short telomeres can cause. It is
thought that
without functional telomerase,
chromosomes will
likely be
attached together at
their ends
through the...
-
reversing it.
Cultures not
containing telomerase-active
pluripotent stem
cells would have been po****ted with
telomerase-inactive cells,
which would have been...
- area of research, it is
generally believed to play a role in
regulating telomerase activity as well as
maintaining the
heterochromatic state at the ends...