-
Telomerase, also
called terminal transferase, is a
ribonucleoprotein that adds a species-dependent
telomere repeat sequence to the 3' end of telomeres...
-
Telomerase reverse transcriptase (abbreviated to TERT, or
hTERT in humans) is a
catalytic subunit of the
enzyme telomerase, which,
together with the telomerase...
- the
University of California,
Santa Cruz.
Greider discovered the
enzyme telomerase in 1984,
while she was a
graduate student of
Elizabeth Blackburn at the...
-
Telomerase RNA component, also
known as TR, TER or TERC, is an
ncRNA found in
eukaryotes that is a
component of
telomerase, the
enzyme used to
extend telomeres...
-
discovery of how
chromosomes are
protected by
telomeres and the
enzyme telomerase.
During DNA replication, DNA
polymerase cannot replicate the sequences...
- Salk
Institute for
Biological Studies. In 1984,
Blackburn co-discovered
telomerase, the
enzyme that
replenishes the telomere, with
Carol W. Greider. For...
- to
activate telomerase more than any
other known compound yet discovered: 8.8-fold. This
exceeds the
activation by
other known telomerase activators:...
- Greider, and Jack
Szostak in the 1980s led to the
successful discovery of
telomerase (the
enzyme responsible for
maintaining telomere length) and a better...
- to
telomerase, an
enzyme that
repairs long
repetitive sections of DNA
sequences at the ends of chromosomes,
referred to as telomeres.
Telomerase is expressed...
- transfusion-dependent anemia.
Imetelstat is an
oligonucleotide telomerase inhibitor. By
blocking telomerase activity,
imetelstat causes telomere shortening, inhibits...
