-
Taxanes are a
class of diterpenes. They were
originally identified from
plants of the
genus Taxus (yews), and
feature a
taxadiene core. Pa****axel (Taxol)...
- (mBC) in
patients who have been
treated previously with
trastuzumab and a
taxane (pa****axel or docetaxel), and who have
already been
treated for mBC or...
- In enzymology, a
taxane 10beta-hydroxylase (EC 1.14.13.76) is an
enzyme that
catalyzes the
chemical reaction taxa-4(20),11-dien-5alpha-yl
acetate + NADPH...
- In enzymology, a
taxane 13alpha-hydroxylase (EC 1.14.13.77) is an
enzyme that
catalyzes the
chemical reaction taxa-4(20),11-dien-5alpha-ol +
NADPH + H+...
- and
include important compounds such as retinol,
phytol or taxadiene.
Taxanes are
class of
diterpenoids featuring a
taxadiene core. They are produced...
- pa****axel or docetaxel. The core
carbon skeleton of a
normal natural product taxane (e.g., pa****axel, docetaxel) has a 6-membered A ring, 8-membered B ring...
-
liver problems. Use
during pregnancy may harm the baby.
Docetaxel is in the
taxane family of medications. It
works by
disrupting the
normal function of microtubules...
-
Taxamairin A is a non-
taxane isolate of
Taxus yunnanensis. Li SH, Zhan HJ, Yao P, Niu XM,
Xiang W, Sun HD (2002). "Non-
taxane compounds from the bark...
-
agents include taxanes and epothilones, both of
which prevent cancer cells from
dividing by
interfering with tubulin.
While taxanes like Pa****axel and...
-
derivative of a
natural taxoid. It is a
microtubule inhibitor, and the
fourth taxane to be
approved as a
cancer therapy.[citation needed]
Cabazitaxel was developed...
