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Taxadiene (taxa-4,11-diene) is a diterpene.
Taxadiene is the
first committed intermediate in the
synthesis of taxol. Six
hydroxylation reactions, and...
-
important compounds such as retinol,
phytol or
taxadiene.
Taxanes are
class of
diterpenoids featuring a
taxadiene core. They are
produced by
plants of the genus...
- The
enzyme taxadiene synthase (EC 4.2.3.17)
catalyzes the
chemical reaction geranylgeranyl diphosphate ⇌ {\displaystyle \rightleftharpoons } taxa-4,11-diene...
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originally identified from
plants of the
genus Taxus (yews), and
feature a
taxadiene core. Pa****axel (Taxol) and
docetaxel (Taxotere) are
widely used as chemotherapy...
- In enzymology, a
taxadiene 5alpha-hydroxylase (EC 1.14.99.37) is an
enzyme that
catalyzes the
chemical reaction taxa-4,11-diene + AH2 + O2 ⇌ {\displaystyle...
-
intermediate known as
taxadiene.
Taxadiene then
undergoes a
series of 10
oxidations via NADPH,
forming the
intermediate taxadiene-5α-acetoxy-10β-ol (multiple...
- is a monoterpenoid, a
tropolone derivative. Humulene, a sesquiterpene.
Taxadiene, a diterpene,
precursor to the
diterpenoid taxol, an
anticancer agent...
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diterpene Sclarene, a
diterpene Stemarene, a
diterpene Stemodene, a
diterpene Taxadiene, a
taxane diterpene This set
index page
lists chemical structure articles...
- C1–C2 bond.
Ongoing research efforts are
directed at the
synthesis of
taxadiene and
taxadienone intermediates. The
synthesis of
related taxanes decinnamoyltaxinine...
-
compounds in
nature Limonene, a monoterpene. Humulene, a sesquiterpene.
Taxadiene, a diterpene,
precursor to the
diterpenoid taxol, an
anticancer agent...
