- The
tankyrases (TNKs) are
PARPs that
comprise ankyrin repeats, an
oligomerization domain (SAM), and a PARP
catalytic domain (PCD).
Tankyrases are also...
-
Tankyrase, also
known as
tankyrase 1, is an
enzyme that in
humans is
encoded by the TNKS gene. It
inhibits the
binding of TERF1 to
telomeric DNA. Tankyrase...
-
Tankyrase-2 is an
enzyme that in
humans is
encoded by the TNKS2 gene. TNKS2 has been
shown to
interact with GRB14, TERF1 and
Cystinyl aminopeptidase....
- tyrosine-protein
kinase LCK PCM1,
Pericentriolar material 1
protein TNKS,
Tankyrase-1 TNKS2,
Tankyrase-2 TUBE1,
Tubulin epsilon chain PCNT, pericentrin, a
matrix scaffold...
-
Immortality Maximum life span
Rejuvenation (aging) Senescence,
biological aging Tankyrase Telomere-binding
protein G-quartet
Immortal DNA
strand hypothesis During...
-
inhibitor 1), TINF2 (TERF1-interacting
telomerase nuclear factor), TNKS2 (
Tankyrase, an enzyme) and NME1 (nucleoside
diphosphate kinase).In conclusion, as...
- 182 kDa
tankyrase-1-binding
protein is an
enzyme that in
humans is
encoded by the TNKS1BP1 gene. TNKS1BP1 has been
shown to
interact with TNKS. GRCh38:...
-
Protein 131 yes TMOD3 TMOD3 Tropomodulin-3 TNKS PARP-5a
Tankyrase TNKS1BP1 TNKS1BP1 182 kDa
tankyrase-1-binding
protein yes TNPO1 Transportin-1 Transportin-1/Karyopherin...
-
telomere lengthening is required, TRF1
recruits helicases and
interacts with
tankyrases to
facilitate the process. TRF1 is
highly expressed in stem cells, and...
- that
results in
decreased proteasome activity. (ADP-ribosyl)transferase
Tankyrase (TNKS)
causes ADP-ribosylation of PI31
which in turn
increases the proteasome...
