- domain-****ociated protein, also
known as
TRRAP, is a
protein that in
humans is
encoded by the
TRRAP gene.
TRRAP belongs to the
phosphatidylinositol 3-kinase-related...
- RuvB-like 1 SAP130 SMAD2 SMAD3 SMARCA4 SMARCB1 SUPT3H TIAM1 TADA2L TAF9 TFAP2A
TRRAP WDR5 YY1 and ZBTB17. C2orf16 Myc-tag C-myc mRNA "Myc". NCBI.
Finver SN,...
- "Transcriptional
activation of
histone genes requires NPAT-dependent
recruitment of
TRRAP-Tip60
complex to
histone promoters during the G1/S
phase transition". Molecular...
-
PIKKs proteins contain the
following four domains: N-terminus FRAP-ATM-
TRRAP (FAT) domain, Pfam PF02259
kinase domain (KD; PI3_PI4_kinase), PIKK- regulatory...
- double-strand DNA
break repair.
Subunits of the
human complex include HTATIP/TIP60,
TRRAP, RUVBL1, RUVBL2, beta-actin and BAF53/ACTL6A. In yeast, the
complex has...
- hADA3 in
activating TP53
function in
response to DNA damage. Similarly,
TRRAP, the
human homolog to
yeast Tra1, has been
shown to
directly interact with...
- are from N-terminus to C-terminus the HEAT
repeat domain, the FRAP-ATM-
TRRAP (FAT) domain, the
kinase domain (KD), the PIKK-regulatory
domain (PRD) and...
- PDK3, PDK4 PMS1, PMS2, PMS2L1, PMS2L11, PMS2L3, PMS4L TOP2A, TOP2B TRAP1,
TRRAP Prodromou C, Roe SM,
Piper PW,
Pearl LH (June 1997). "A
molecular clamp...
- (Oct 2003). "Identification of new
subunits of the
multiprotein mammalian TRRAP/TIP60-containing
histone acetyltransferase complex". J Biol Chem. 278 (44):...
-
works later in the DNA
repair process, as it
serves as a
cofactor for
TRRAP.
TRRAP enhances DNA
remodeling by
binding to
chromatin near
broken double stranded...
