- the
reaction will be
catalyzed by phenylalanine-tRNA
synthase to
produce tRNAphe. The
other end—the
bottom often called the "DNA arm"—consists of a three...
-
reaction ATP + L-phenylalanine +
tRNAPhe ⇌ {\displaystyle \rightleftharpoons } AMP +
diphosphate + L-phenylalanyl-
tRNAPhe The 3
substrates of this enzyme...
- The
cloverleaf structure of
Yeast tRNAPhe (inset) and the 3D
structure determined by X-ray analysis....
- Kim et al.
achieved another breakthrough,
producing crystals of
yeast tRNAPHE that
diffracted to 2–3 Ångström
resolutions by
using spermine, a naturally...
-
Mancuso M,
Filosto M,
Mootha VK, et al. (June 2004). "A
novel mitochondrial tRNAPhe mutation causes MERRF syndrome". Neurology. 62 (11): 2119–21. doi:10.1212/01...
- the
overall pairing geometry of
anticodons of tRNA. As an example,
yeast tRNAPhe has the
anticodon 5'-GmAA-3' and can
recognize the
codons 5'-UUC-3' and...
- the two helices.
Coaxial stacking was
noted in the
crystal structure of
tRNAPhe. More recently,
coaxial stacking has been
observed in
higher order structures...
-
outcome of hypermodification. This
hypermodification at
position 37 of
tRNAPhe may
allow for base-
stacking interactions which play a key role in maintenance...
-
Nyborg J (December 1995). "Crystal
structure of the
ternary complex of Phe-
tRNAPhe, EF-Tu, and a GTP analog". Science. 270 (5241): 1464–72. doi:10.1126/science...
- As
early as in the 1970s,
analysis of the
crystal structure of
yeast tRNAPhe showed that RNA
structures possess significant non-canonical variations...
