-
Trimethylsilyl trifluoromethanesulfonate (
TMSOTf) is an
organosilicon compound with the
formula (CH3)3SiO3SCF3. It is a
colorless moisture-sensitive liquid...
- cyanide,
trimethylsilyl azide, and
trimethylsilyl trifluoromethanesulfonate (
TMSOTf).
These compounds are
produced by a salt
metathesis reaction between trimethylsilyl...
-
Trimethylsilyl chloride (TMSCl) or
trimethylsilyl trifluoromethanesulfonate (
TMSOTf) and base (i.e. pyridine, triethylamine, or 2,6-lutidine) in dichloromethane...
- epicatechin-(4β-8)-catechin-(4α-8)-epicatechin
trimer derivatives) can be
achieved with
TMSOTf-catalyzed
condensation reaction, in
excellent yields. The
structure of benzylated...
- is
further reacted with
trimethylsilyl trifluoromethanesulfonate (
TMSOTf)
under the silyl-Hilbert–Johnson
reaction and
deprotected by an acid or...
-
although other polar solvents are also common.
Workup of
reactions employing TMSOTf involves treatment with an ice-cold
solution of
sodium bicarbonate and extraction...
- for
glycosylation reactions using trichloroacetimidates are BF 3•OEt 2 or
TMSOTf.
Column chromatographic purification of the
reaction mixture can sometimes...
- epicatechin-(4β-8)-catechin-(4α-8)-epicatechin
trimer derivatives) can be
achieved with
TMSOTf-catalyzed
condensation reaction, in
excellent yields. The
structure of benzylated...
-
tosylation (TsCl, DMAP) to 24,
deprotection to diol (TBAF) and
reprotection (
TMSOTf, 2,6-lutidine, DIPEA) as TMS
ether 25, Ley
oxidation to
aldehyde 26, cyanohydrin...
