- A
synaptosome is an
isolated synaptic terminal from a neuron.
Synaptosomes are
obtained by mild
homogenization of
nervous tissue under isotonic conditions...
- Nomifensine,
formerly sold
under the
brand names Merital and Alival, is a norepinephrine–dopamine
reuptake inhibitor (NDRI) drug that was
developed in...
-
inhibits glutamate release,
calcium uptake and also
glutamate uptake in
synaptosomes. Currently, it is
known to
naturally occur only in the
venom of the spider...
- drug
releases the neurotransmitter. The ****ays were done in rat
brain synaptosomes and
human potencies may be different. See also
Monoamine releasing agent...
- half-maximal
effective concentration values of 190 nM and 620 nM in rat
brain synaptosomes,
whereas norepinephrine release was not reported. In
contrast to many...
-
techniques to
brain tissue permitted the
isolation first of
nerve endings (
synaptosomes), and
subsequently of
synaptic vesicles from
mammalian brain. Two competing...
- M,
Mennini T (April 1999). "Release
studies with rat
brain cortical synaptosomes indicate that
tramadol is a 5-hydroxytryptamine
uptake blocker and not...
- drug
releases the neurotransmitter. The ****ays were done in rat
brain synaptosomes and
human potencies may be different. See also
Monoamine releasing agent...
- proteins,
synaptosomes possess all of the
cellular machinery necessary for
neurotransmitter synthesis, release, metabolism, and reuptake.
Synaptosomes, however...
- norepinephrine, 590 nM for dopamine, and 12,860 nM for
serotonin in rat
brain synaptosomes. α-Methylmethcathinone was
first described in the
scientific literature...
