-
Synaptobrevins (
synaptobrevin isotypes 1-2) are
small integral membrane proteins of
secretory vesicles with
molecular weight of 18
kilodalton (kDa) that...
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light chain is then free to
cleave the Gln76-Phe77 bond of
synaptobrevin.
Cleavage of
synaptobrevin affects the
stability of the
SNARE core by restricting...
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layer in the ****embled core
SNARE complex. One
particular R-SNARE is
synaptobrevin,
which is
located in the
synaptic vesicles. Q-SNAREs are
proteins that...
- 2 (VAMP2) is a
protein that in
humans is
encoded by the VAMP2 gene.
Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-****ociated
protein SNAP25...
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docking of
synaptic vesicles in an ATP-dependent manner. With the help of
synaptobrevin on the
synaptic vesicle, the t-SNARE
complex on the membrane, made up...
- The core
SNARE complex is
formed by four α-helices
contributed by
synaptobrevin,
syntaxin and SNAP-25,
synaptotagmin serves as a
calcium sensor and...
- of a
vesicle with the cell
membrane to
initiate an
exocytotic event.
Synaptobrevin, a
protein that is a part of the vesicle-****ociated
membrane protein...
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specifically cleave the SNAP-25,
whereas serotype B, D, F and G cut
synaptobrevin.
Serotype C
cleaves both SNAP-25 and syntaxin. This
causes blockade...
- cytosol,
where it
cleaves vesicle ****ociated
membrane protein (VAMP)
synaptobrevin,
which is
necessary for
membrane fusion of
small synaptic vesicles (SSV's)...
- SNAP-25 and syntaxin-1,
which later accommodates synaptobrevin-2 (the
quoted syntaxin and
synaptobrevin isotypes parti****te in
neuronal neuromediator release)...