-
Swinholides are
dimeric 42 carbon-ring
polyketides that
exhibit a 2-fold axis of symmetry.
Found mostly in the
marine sponge Theonella,
swinholides encomp****...
- Hong, Suckchang; Krische,
Michael J. (2016-11-02). "Total
Synthesis of
Swinholide A: An
Exposition in Hydrogen-Mediated C–C Bond Formation".
Journal of...
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complexed with ATP-actin 1yxq:
Crystal structure of
actin in
complex with
swinholide A 2a3z:
Ternary complex of the WH2
domain of WASP with Actin-DNAse I 2a40:...
-
complexed with ATP-actin 1yxq:
Crystal structure of
actin in
complex with
swinholide A 2a3z:
Ternary complex of the WH2
domain of WASP with Actin-DNAse I 2a40:...
- ISBN 978-3-642-04608-7. Bubb MR,
Spector I,
Bershadsky AD, Korn ED (February 1995). "
Swinholide A is a
microfilament disrupting marine toxin that
stabilizes actin dimers...
-
complexed with ATP-actin 1yxq:
Crystal structure of
actin in
complex with
swinholide A 2a3z:
Ternary complex of the WH2
domain of WASP with Actin-DNAse I 2a40:...
- a
diverse set of
biologically active natural products,
including the
swinholides and polytheonamides. It
bears structural similarities to the pederins...
-
crotylation was used by
Krische to
prepare 6-deoxyerythronolide B and
swinholide A.
Organostannane addition Carbonyl allylation Kim, In Su; Ngai, Ming-Yu;...
-
complexed with ATP-actin 1yxq:
Crystal structure of
actin in
complex with
swinholide A 2a3z:
Ternary complex of the WH2
domain of WASP with Actin-DNAse I 2a40:...
-
shown to
increase step-economy. For example, a
concise total synthesis of
swinholide A was
achieved using diverse hydrogen-mediated C-C couplings. NSF-CAREER...